Collection Pack
Collection Pack
Early Detection of Alzheimer's Disease with the p-Tau217 Biomarker

Specimen Type: Plasma

Turnaround Time: 14 Days

Not available in New York state.

Only healthcare providers licensed in their state may order laboratory testing. 

Turnaround times are estimates. Detailed order tracking is available in myGDX.

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Why choose Genova Diagnostics’ Alzheimer’s Assessment?

Groundbreaking
Biomarker Detection

Utilizes the groundbreaking p-Tau217 biomarker for early and accurate detection of Alzheimer's disease (AD).1 

Convenient and
Cost-Effective

A simple blood draw makes testing more accessible and cost-effective compared to lumbar puncture or imaging studies.

Highly Accurate
Results

p-Tau217 shows a strong correlation with PET imaging and cerebrospinal fluid (CSF) testing, ensuring highly accurate results.1

Genova's Alzheimer's Assessment measures plasma p-Tau217, a specific protein identified as a reliable biomarker to aid in diagnosing Alzheimer’s disease (AD).1 This assay helps detect AD pathology, including extracellular amyloid-beta plaques and intracellular neurofibrillary tangles of hyperphosphorylated tau (p-tau), before the onset of clinical symptoms.

Who should test?

The Alzheimer's Assessment is intended for adult patients aged 45 and older who present with cognitive impairment and are being evaluated for AD or other causes of cognitive decline.

There are comorbid conditions that may affect phosphorylated tau levels in the blood. These can include conditions affecting hepatic and renal function, such as chronic kidney disease (CKD), as well as a history of stroke or myocardial infarction. Certain medications to support kidney function may also play a role in heightened levels of p-Tau217. Additionally, differences in results based on racial and ethnic background, sex, and age have not yet been established.

 

References
  1. Ashton NJ, Brum WS, Di Molfetta G, et al. Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology. JAMA Neurol. 2024;81(3):255-263.
 

Support Materials

Collection Instructions
Sample Report

 

Genova's Alzheimer's Assessment measures plasma p-Tau217, a specific protein identified as a reliable biomarker to aid in diagnosing Alzheimer’s disease (AD).1 This assay helps detect AD pathology, including extracellular amyloid-beta plaques and intracellular neurofibrillary tangles of hyperphosphorylated tau (p-tau), before the onset of clinical symptoms.

Who should test?

The Alzheimer's Assessment is intended for adult patients aged 45 and older who present with cognitive impairment and are being evaluated for AD or other causes of cognitive decline.

There are comorbid conditions that may affect phosphorylated tau levels in the blood. These can include conditions affecting hepatic and renal function, such as chronic kidney disease (CKD), as well as a history of stroke or myocardial infarction. Certain medications to support kidney function may also play a role in heightened levels of p-Tau217. Additionally, differences in results based on racial and ethnic background, sex, and age have not yet been established.

 

References
  1. Ashton NJ, Brum WS, Di Molfetta G, et al. Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology. JAMA Neurol. 2024;81(3):255-263.
 

Support Materials

Collection Instructions
Sample Report

 

How it Works

Consult Doctor

Your doctor will discuss your symptoms and help decide which test is right for you.

Many specimen collections can be completed from the privacy of your home.

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Activate Test

Collection packs can be dropshipped directly to your home and everything you need to begin testing is included.

Already have a collection pack? Activate your test and begin today.

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Collect Samples

Use a calendar to plan for your collection.

Follow instructions carefully and be sure to add important details about you and your specimens in the Activation portal.

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Ship to Lab

Ship your specimens using the prepaid FedEx materials provided.

Results are available online. Schedule time with your physician to review results and create a plan for your health.

FAQ

Review information on the Test Preparation tab above for details on how medications and supplements may impact this test.

We provide a variety of testing services, and some of them may or may not be covered by your insurance plan.

Once your physician has ordered a Genova Diagnostics test for you, you can submit the CPT codes for your test to your commercial insurance plan to determine coverage. For information about billing options, please visit the Billing Information page.

Support guides, charts, and additional aids can be found on the Support Materials tab. Additional educational materials can be found in our Learning Library.

Genova also offers complimentary Medical Education Consultations for healthcare providers. Schedule consults online by signing in to your myGDX account.