Genova Diagnostics
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Collection Pack
Collection Pack
Early Detection of Alzheimer's Disease with the p-Tau217 Biomarker

Specimen Type: Plasma

Turnaround Time: 14 Days

Turnaround times are estimates. Detailed order tracking is available in myGDX.

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Why choose Genova Diagnostics' Alzheimer's Assessment?

Groundbreaking
Biomarker Detection

Utilizes the groundbreaking p-Tau217 biomarker for early and accurate detection of Alzheimer's disease (AD).1 

Convenient and
Cost-Effective

A simple blood draw makes testing more accessible and cost-effective compared to lumbar puncture or imaging studies.

Highly Accurate
Results

p-Tau217 shows a strong correlation with PET imaging and cerebrospinal fluid (CSF) testing, ensuring highly accurate results.1

Genova's Alzheimer's Assessment measures plasma p-Tau217, a specific protein identified as a reliable biomarker to aid in diagnosing Alzheimer's disease (AD).1 This assay helps detect AD pathology, including extracellular amyloid-beta plaques and intracellular neurofibrillary tangles of hyperphosphorylated tau (p-tau), before the onset of clinical symptoms.

Who should test?

The Alzheimer's Assessment is intended for adult patients aged 45 and older who present with cognitive impairment and are being evaluated for AD or other causes of cognitive decline.

There are comorbid conditions that may affect phosphorylated tau levels in the blood. These can include conditions affecting hepatic and renal function, such as chronic kidney disease (CKD), as well as a history of stroke or myocardial infarction. Certain medications to support kidney function may also play a role in heightened levels of p-Tau217. Additionally, differences in results based on racial and ethnic background, sex, and age have not yet been established.

 

References
  1. Ashton NJ, Brum WS, Di Molfetta G, et al. Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology. JAMA Neurol. 2024;81(3):255-263.
 

Support Materials

Collection Instructions
Sample Report

 

Genova's Alzheimer's Assessment measures plasma p-Tau217, a specific protein identified as a reliable biomarker to aid in diagnosing Alzheimer's disease (AD).1 This assay helps detect AD pathology, including extracellular amyloid-beta plaques and intracellular neurofibrillary tangles of hyperphosphorylated tau (p-tau), before the onset of clinical symptoms.

Who should test?

The Alzheimer's Assessment is intended for adult patients aged 45 and older who present with cognitive impairment and are being evaluated for AD or other causes of cognitive decline.

There are comorbid conditions that may affect phosphorylated tau levels in the blood. These can include conditions affecting hepatic and renal function, such as chronic kidney disease (CKD), as well as a history of stroke or myocardial infarction. Certain medications to support kidney function may also play a role in heightened levels of p-Tau217. Additionally, differences in results based on racial and ethnic background, sex, and age have not yet been established.

 

References
  1. Ashton NJ, Brum WS, Di Molfetta G, et al. Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology. JAMA Neurol. 2024;81(3):255-263.
 

Support Materials

Collection Instructions
Sample Report

 

How it Works

Consult Healthcare Provider

Your provider will discuss your symptoms and help decide which test is right for you.

Many specimen collections can be completed from the privacy of your home.

Collect Samples

Use a calendar to plan for your collection.

Follow instructions carefully and be sure to add important details about you and your specimens where indicated.

Ship to Lab

Ship specimens using the materials provided.

Schedule time with your healthcare provider to review results and create a plan for your health.